CURRICULUM VITAE
Hong-mei Wang
Department of Neurology, Sixth People’s Hospital
Shanghai Jiao Tong University
600 Yi Shan Road, Shanghai, 200233
EDUCATION
2010 Ph.D. in Neurology
Shanghai Jiaotong University, Shanghai, China
2004 M.M. in Neurology
Xuzhou medical Universiy, Jiangsu province, China
ACADEMIC AWARDS
2009-2010 Shanghai Jiao Tong University School of Medicine Graduate Merit Scholarship Award
RESEARCH INTERESTS
The mechanisms of Alzheimer’s and Parkinson’s diseases both in basic and clinical fields
PROJECTS
National Natural Science Foundation of China (811000953) 2012.1-2014.12
Visiting Scholar Program, Project of Shanghai Municipal Education Commission 2013-2014
PUBLICATIONS
[1]Zhang T#,
Wang HM#, Li Q, Huang JK, Sun XJ.
Modulating autophagy affects neuroamyloidogenesis in an in vitro ischemic stroke model. Neuroscience. 2014;263:130-137.
[2]
Wang HM, Zhang T, Huang JK, Sun XJ. 3-n-butylphthalide (NBP) attenuates the amyloid-beta-induced inflammatory responses in cultured astrocytes via the
nuclear factor-κB signaling pathway. Cell Physiol Biochem.2013;32:235-242.
[3]
Wang HM, Zhang T, Li Q, Huang JK, Chen RF, Sun XJ. Inhibition of glycogen synthase kinase-3β by lithium chloride suppresses 6-hydroxydopamine-induced inflammatory response in primary cultured astrocytes.
Neurochem Int.2013;63(5):345-353.
[4]Curcumin ameliorates the neurodegenerative pathology in A53T α-synuclein cell model of Parkinson's disease through the downregulation of mTOR/p70S6K
signaling and the recovery of macroautophagy.J Neuroimmune Pharmacol. 2013; 8(1):356-69.
[5]Gui YX, Fan XN,
Wang HM, Wang G, Chen SD.
Glyphosate induced cell death through apoptotic and autophagic mechanisms.Neurotoxicol Teratol.2012; 34(3):344-9.
[6]
Wang HM, Zhao YX, Zhang S, Liu GD, Kang WY, Tang HD, Ding JQ, Chen SD.PPARgamma agonist curcumin reduces the amyloid-beta-stimulated inflammatory responses in primary astrocytes.J Alzheimers Dis.2010;20(4):1189-99.
[7]
Wang HM, Ma JF, Tan YY, Wang ZQ, Sheng CY, Chen SD, Ding JQ.Amyloid-beta1-42 induces reactive oxygen species-mediated autophagic cell death in U87 and SH-SY5Y cells.J Alzheimers Dis. 2010;21(2):597-610.
[8]Ma JF#,
Wang HM#, Li QY, Zhang Y, Pan J, Qiang Q, Xin XY, Tang HD, Ding JQ, Chen SD. Starvation triggers Abeta42 generation from human umbilical vascular endothelial cells. FEBS Lett. 2010; 584(14):3101-6.
[9]
Li QY,
Wang HM,
Wang ZQ,
Ma JF,
Ding JQ,
Chen SD. Salidroside attenuates hypoxia-induced abnormal processing of amyloid precursor protein by decreasing BACE1 expression in SH-SY5Y cells.
Neurosci Lett. 2010;481(3):154-8.